Ulipristal acetate decreases active TGF-β3 and its signaling through up-regulation of fibrillin
نویسندگان
چکیده
منابع مشابه
Ulipristal Acetate (ella)
INTRODUCTION In the U.S., it is estimated that onehalf of the six million pregnancies that occur each year are unplanned or un expected.1 Despite the widespread of use of various contraceptive methods, including hormonal contraceptive tablets and condoms, these methods remain imperfect. Inadequate contraceptive use or failure of a contraceptive method, in addition to unprotected sexual intercou...
متن کاملUlipristal acetate emergency contraception.
I read with interest the letter by Webb et al. about the pitfalls of adapting the Clinical Effectiveness Unit’s guidance on emergency contraception (EC). Their letter discusses, in relation to maximising the pharmacodynamic attributes of ulipristal acetate (UA), the significant inaccuracies inherent in the calculation of the timing of ovulation based on the menstrual history. However, we freque...
متن کاملEconomic impact of ulipristal acetate
Objective To assess the budget impact of using ulipristal acetate (UPA) 5 mg to treat women with uterine fibroids (UF) causing moderate to severe symptoms. Design We modelled trends in the number of surgical procedures for symptomatic UF, with and without the use of UPA for preoperative or intermittent treatment and assessed the budget impact of UPA use from the French national healthcare insur...
متن کاملUlipristal acetate in emergency contraception.
Despite the widespread availability of highly effective methods of contraception, unintended pregnancy is common. Unplanned pregnancies have been linked to a range of health, social and economic consequences. Emergency contraception reduces risk of pregnancy after unprotected intercourse, and represents an opportunity to decrease number of unplanned pregnancies and abortions. Emergency contrace...
متن کاملDcR3 induces epithelial-mesenchymal transition through activation of the TGF-β3/SMAD signaling pathway in CRC
Decoy receptor 3 (DcR3), a novel member of the tumor necrosis factor receptor (TNFR) family, was recently reported to be associated with tumorigenesis and metastasis. However, the role of DcR3 in human colorectal cancer (CRC) has not been fully elucidated. In this study, we found that DcR3 expression was significantly higher in human colorectal cancer tissues than in paired normal tissues, and ...
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ژورنال
عنوان ژورنال: Fertility and Sterility
سال: 2018
ISSN: 0015-0282
DOI: 10.1016/j.fertnstert.2018.07.405